Of course, the only real way to deal with Progenitus is with a board wipe of some kind, but, even then, if it goes into the graveyard you just shuffle it back into your deck
This card is probably just for the diehard Unfinity fans
some control decks rely primarily on black removal and disruption instead, for example
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Magic has more than enough self-mill to facilitate a swift flip, and I highly doubt you need much more than that to win with the proper setup
Ravenloft Adventurer Ah, Battle for Baldurs Gate and those initiative plays